Inflammatory Breast Cancer Treatment, Hyperthermia Holistic Center Case II

Home Up Table of Contents Search Links Inform Request

ADENOCARCINOM CANCER / AIDS LYMPHOMA CANCER / BRAIN CANCER TUMOR / BREAST CANCER / SINUS SARCOMA CANCER
  INFLAMMATORY BREAST CANCE (IBC) TUMOR / PROSTATE CANCER TUMOR / TONSIL CANCER TUMOR / NECK CANCER TUMOR I
NECK CANCER TUMOR II / BREAST CANCER, HEAD and NECK TUMOR, DEEP TUMORS

Inflammatory Breast Cancer treatment, IBC    Case I

Inflammatory Breast Cancer (IBC) Treatment

Inflammatory Breast Cancer (IBC), Case II

One patient results. These MRI were taken before and after the Inflammatory Breast Cancer treatment with Hyperhermia, combined with low radiation dose.

                   Before treatment, 11·12·97                             After treatment, 03·18·98
Inflammatory Breast Cancer Treatment - Enhanced MRI
Enhanced MRI. Arrows point at area of Inflammatory Breast Cancer involvement ( yellow areas ).

 anabull1.gif (2533 bytes)  Inflammatory Breast Cancer Treatment - set up picture  Ultrasound Treatment Set Up   

 anabull1.gif (2533 bytes)  Inflammatory Breast Cancer Treatment - set up picture 2   Microwave Treatment Set Up 

You are visitor No.: Hit Counter
WB01337_.gif (904 bytes)                                  Top of Page / Home / Treatment Results / Back

MORE HEAT AND LESS RADIATION.

HYPERFRACTIONATION IS KEY IN THE SUCCESFUL TREATMENT OF MALIGNANT TUMORS

James I. Bicher, M. D.

Valley Cancer Institute, Los Angeles, CA, U.S.A

 

Hyperthermia has been proven to increase the response of malignant tumors to radiation therapy in both experimental animal tumors and the clinical treatment of human cancer. Based on our multi-year experience, first in re-treatment of previously radiated fields that necessitated the use of low dose radiation fractions as adjunct to the heat treatments, and then progressively applying the encouraging results obtained to areas treated "de novo" and eventually to situations allowing a potentially curative intent, treatment protocols have been devised and tested that yield positive preliminary data showing superior tumor response rates and less side effects when compared with historical controls at our Institute.

The hyperthermia part of the protocol extends the number of heat treatments to correspond to the number of radiation-fractions, as each hyperthermia treatment proceeds or follows each radiation treatment in close time proximity. The number of hyperthermia treatments therefore varies from 25-50 per course for each treated field.

The radiation protocol consists of progressively decreasing daily doses of radiation therapy combined with the daily hyperthermia treatments. Typically the treatment is started at a daily dose of 180cGy gradually reduced to 100cGy protracting a typical radiation therapy treatment course from 5000cGy in five weeks to 5000cGy given in over eight weeks; or 7000cGy in seven weeks to 7000cGy in 14 weeks. According to the ELLIS TDF formula, this results in a 15% or 25% reduction of the effective radiation dose. The total dose is of course adapted to the clinical situation.

The following Conclusions are drawn:

Protracted Hyperfractionation

  1. Decreases the radiation dose by 15% and 24%.
  2. Decreases the side effects of XRT (no diarrhea, fistula or pneumonitis in PH cases)
  3. Allows for more combined XRT-Hyperthermia treatments
  4. Increases the effectiveness of the combined treatment in superficial and deep tumors.

Question: What is the lowest radiation dose needed to potentiate Hyperthermia?

 

[ Home ] [ Up ][Links]
Search engine optimization by SeOS

General Information: inforequest@vci.org

Last modified: May 06, 2008